Motif ID: NFY{A,B,C}.p2

Z-value: 2.160


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409770920.572.0e-02Click!
NFYAchr6_+_411486910.533.6e-02Click!
NFYBchr12_-_103055924-0.204.5e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_48934831 3.359


chr19_+_19035792 3.251 NM_178526
 SLC25A42
solute carrier family 25, member 42
chr14_+_23654161 2.905 DCAF11
DDB1 and CUL4 associated factor 11
chr14_-_73620826 2.903 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_+_23654307 2.898 NM_181357
 DCAF11
DDB1 and CUL4 associated factor 11
chr2_+_69995740 2.801 MXD1
MAX dimerization protein 1
chr17_+_78009895 2.757 NARF
nuclear prelamin A recognition factor
chr17_+_54587882 2.676 PRR11
proline rich 11
chr17_+_78009819 2.576 NM_001083608
NM_012336
NM_031968
 NARF


nuclear prelamin A recognition factor


chr2_-_239987629 2.556 HDAC4
histone deacetylase 4
chr19_+_63482118 2.479 NM_021089
 ZNF8
zinc finger protein 8
chr1_-_109742020 2.478 NM_002959
 SORT1
sortilin 1
chr3_+_187771139 2.447 NM_016306
 DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr3_+_187771192 2.446 DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr14_+_23653848 2.268 DCAF11
DDB1 and CUL4 associated factor 11
chr20_-_45418818 2.260 NM_012408
NM_183047
NM_183048
 ZMYND8


zinc finger, MYND-type containing 8


chr2_+_203207912 2.254 FAM117B
family with sequence similarity 117, member B
chr1_+_42920683 2.241 YBX1
Y box binding protein 1
chr2_+_69995807 2.203 MXD1
MAX dimerization protein 1
chr14_+_103251798 2.132 NM_001198953
NM_024071
 ZFYVE21

zinc finger, FYVE domain containing 21


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 116 entries
enrichment   p-value GO term description
7.27 1.34e-02 GO:0002566 somatic diversification of immune receptors via somatic mutation
7.27 1.34e-02 GO:0016446 somatic hypermutation of immunoglobulin genes
4.81 1.82e-05 GO:0006695 cholesterol biosynthetic process
4.67 3.67e-02 GO:0006298 mismatch repair
4.07 4.23e-04 GO:0016126 sterol biosynthetic process
4.01 3.64e-02 GO:0006271 DNA strand elongation involved in DNA replication
3.95 1.47e-04 GO:0000819 sister chromatid segregation
3.94 3.94e-10 GO:0000236 mitotic prometaphase
3.78 1.54e-03 GO:0000070 mitotic sister chromatid segregation
3.77 9.18e-12 GO:0007059 chromosome segregation
3.10 2.09e-21 GO:0000087 M phase of mitotic cell cycle
3.06 1.88e-06 GO:0065004 protein-DNA complex assembly
3.02 2.93e-19 GO:0000280 nuclear division
3.02 2.93e-19 GO:0007067 mitosis
3.01 4.44e-05 GO:0006334 nucleosome assembly
2.99 1.39e-07 GO:0006323 DNA packaging
2.98 2.46e-06 GO:0071824 protein-DNA complex subunit organization
2.96 4.33e-05 GO:0031497 chromatin assembly
2.95 4.56e-02 GO:0000910 cytokinesis
2.93 3.48e-18 GO:0048285 organelle fission

Gene overrepresentation in compartment category:

Showing 1 to 20 of 69 entries
enrichment   p-value GO term description
7.79 3.81e-02 GO:0032389 MutLalpha complex
7.48 3.12e-04 GO:0008250 oligosaccharyltransferase complex
6.80 1.04e-03 GO:0000780 condensed nuclear chromosome, centromeric region
6.23 2.82e-03 GO:0032300 mismatch repair complex
4.08 2.01e-07 GO:0000794 condensed nuclear chromosome
3.47 3.19e-07 GO:0000779 condensed chromosome, centromeric region
3.33 6.94e-06 GO:0000777 condensed chromosome kinetochore
3.27 6.77e-12 GO:0000793 condensed chromosome
3.26 5.43e-07 GO:0000776 kinetochore
3.21 1.02e-04 GO:0000922 spindle pole
3.20 1.74e-11 GO:0000775 chromosome, centromeric region
3.17 4.43e-04 GO:0000786 nucleosome
3.02 5.97e-04 GO:0034399 nuclear periphery
2.91 1.27e-10 GO:0044454 nuclear chromosome part
2.86 7.62e-03 GO:0016363 nuclear matrix
2.84 2.42e-02 GO:0016605 PML body
2.76 1.98e-11 GO:0000228 nuclear chromosome
2.73 2.18e-12 GO:0000785 chromatin
2.70 3.15e-04 GO:0032993 protein-DNA complex
2.64 2.71e-27 GO:0005694 chromosome

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
8.01 7.20e-03 GO:0032404 mismatch repair complex binding
7.27 3.57e-03 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
6.54 1.08e-02 GO:0004576 oligosaccharyl transferase activity
6.01 1.66e-03 GO:0030983 mismatched DNA binding
3.19 4.01e-02 GO:0003678 DNA helicase activity
2.86 1.16e-02 GO:0019902 phosphatase binding
1.83 1.84e-02 GO:0048037 cofactor binding
1.53 1.34e-03 GO:0019899 enzyme binding
1.44 2.05e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.43 4.65e-02 GO:0017111 nucleoside-triphosphatase activity
1.42 4.29e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.41 4.03e-09 GO:0003677 DNA binding
1.37 1.53e-11 GO:0003676 nucleic acid binding
1.36 7.48e-04 GO:0030554 adenyl nucleotide binding
1.36 8.44e-04 GO:0005524 ATP binding
1.36 1.13e-03 GO:0032559 adenyl ribonucleotide binding
1.32 4.98e-05 GO:0000166 nucleotide binding
1.30 4.57e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.29 5.80e-03 GO:0017076 purine nucleotide binding
1.29 7.62e-03 GO:0032553 ribonucleotide binding